All this causes volatility which has made biotech famous (or infamous!). During these sell-offs, mid-size companies with no revenues tend do get hurt the most. If you have invested in these stocks, you should have expected and prepared for such a day. In the remainder of this post, I will review what has happened to my portfolio and what I intend to do with each position. The dominant theme is to wait until the summer.
AMGN: $60.11 , Market cap = $70 B , My rating: Sell
The FDA ruling that their anemia drugs at high doses are dangerous in cancer patients will have direct impact on sales. The effect of this is uncertain, but until then, the stock will go down or sideways. Although, there is a chance that most of the bad news is already priced in at these levels, but I just don't see any near term catalysts to make up the lost revenues.
CEPH is expected to earn between $3.3 and $4.2/share in 2007 which puts its PE between 15 and 19. The stock is very cheap at these levels and should be considered a gift.
CELG: $51.5, Market cap = $19.4 B My Rating: Neutral
Back in December, I thought CELG was too expensive. After a 15% correction, it is still trading at about 25X earnings. I think CELG will have a difficult time breaking the $20 Billion market cap barrier unless they get approval of Revlimide in other indications. The company may have competition for Thalidomide in the near future. I would consider buying it below $45 if the fundamentals are still good.
BIIB: $44.3, Market cap = $15 B, My Rating: Neutral
Tysabri sales growth is the only near term catalyst for BIIB. I have been bullish about it's prospects but until revenues are released later this year, I would stay away. Still, it is hard to not to own a company with $3 billion in revenues and lots of cash considering CELG is trading higher with much less revenues.AMLN: $38.5, Market cap =$5 B My Rating: Buy
I still think Byetta will be a success story. I think the fears of competition from newer drugs are overblown. The chart shows nice support around $35.
VRTX: $27.8, Market cap = $3.4 B My Rating: Buy
(VRTX is a great example of a stock not to own during a market sell off. It looks like it is headed to $25 or even lower. When wall street collectively decides to fly to safety, stocks with no earnings get hammered. With the case of VRTX however, this is way overdone (almost a 50% drop in three months!). The catalyst for this stock is the release of clinical trial updates which is less than a month away. If the results are good, the stock will take off and end the year around $40. If you have access to options, it would be a great idea to hedge the position by purchasing some puts. I liked this stock at $35 and I like it even more here at $27. Given the possibility of further declines, I would save some cash to buy lower or hedge with puts. In the longer term, this is my favorite biotech company as I anticipate that they will dominate the HCV therapy market for years to come with Telapravir and the second generation product! I also like VPHMViropharma) because they have a complementary product ( polymerase inhibitor) that may be used in a cocktail with Telepravir to make the treatment more effective. Of course the clinical trials are years away.
ALTU: $13.7, Market cap = $350 M, My Rating: Buy
ALTU has two promising Phase II products and Genentech as a partner which will pick up the cost of Phase III trials for Growth Hormone product. The stock may be very volatile this year but it should trade in the $20's by the end of the year of the phase II trials are successful.
ARNA recently announced initiation of a Phase II clinical trial for an insomnia drug. They are already in a lengthy and expensive Phase III trial for an obesity drug. The additional costs may force ARNA to sell more shares to raise money which would be dilutive and lead to lower prices. However, I believe ARNA will announce a partnership with a big pharmaceutical company before year's end.Bottom Line: I would not recommend to go an d buy any of these stocks until this summer. If had to buy any biotech stocks today it would be CEPH. For the rest, you can be patient and wait for the overall market to improve!